Anti-AMPK beta 2 Mouse mAb

Primary Antibodies

Uncategorized

Ambient temperature

Stable for 12 months from date of receipt/reconstitution.

AMPK beta2 is a subunit of AMP-activated protein kinase (AMPK), which is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia. The tumor suppressor LKB1, in association with accessory proteins STRAD and MO25, phosphorylates AMPKα at Thr172 in the activation loop, and this phosphorylation is required for AMPK activation.

PBS, Glycerol, BSA

Recombinant Monoclonal

cytoplasm, Nucleus