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Anti-Histone H3 Rabbit mAb (HRP Conjugate)

ArtNr PTM-6621
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB, IHC-P
Clon 8-H2L4
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag HRP
Citations Jiabin Zheng, et al. KDM3A Ablation Activates Endogenous Retrovirus Expression to Stimulate Antitumor Immunity in Gastric Cancer. Advanced Science, 2024. https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202309983.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Histone H3.1,Histone H3/a,H3C1,H3FA,HIST1H3A,Histone H3/b,Histone H3/c,Histone H3/d
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Histone & Histone Modification Antibodies, Loading Control Antibodies
Manufacturer - Targets
Histone H3
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight
15
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Epigenetics
Product description
The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. It is an important protein in the emerging field of epigenetics, where its sequence variants and variable.
Purification Method
Protein A purified
Manufacturer - Specificity
Anti-Histone H3 Rabbit mAb (HRP Conjugate) detects endogenous levels of total histone H3 protein. It does not cross-react with other histone or non-histone proteins.
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Immunogen
Synthetic peptide corresponding to the N-terminus of human histone H3 protein
Clonality
Recombinant Monoclonal
Background
The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. It is an important protein in the emerging field of epigenetics, where its sequence variants and variable.
Cellular Localization
Nucleus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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