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Anti-CD11b Mouse mAb

ArtNr PTM-6625
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen FC
Clon 11909
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
CD11b
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Cancer, Immunology
Product description
CD11b, also named as integrin alpha M (ITGAM), is a transmembrane protein forming heterodimers that are composed of α and β subunits. CD11b is expressed by, and commonly used as a marker for, myeloid lineage cells, including neutrophils, monocytes, macrophages, and microglia. CD11b is phosphorylated at Ser1126 (cytoplasmic tail) in neutrophils. Phosphorylation plays a role for leukocytes traveling from the blood stream to tissues. Furthermore, genome-wide association studies have linked CD11b to autoimmune diseases, such as systemic lupus erythematous (SLE).
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
CD11b, also named as integrin alpha M (ITGAM), is a transmembrane protein forming heterodimers that are composed of α and β subunits. CD11b is expressed by, and commonly used as a marker for, myeloid lineage cells, including neutrophils, monocytes, macrophages, and microglia. CD11b is phosphorylated at Ser1126 (cytoplasmic tail) in neutrophils. Phosphorylation plays a role for leukocytes traveling from the blood stream to tissues. Furthermore, genome-wide association studies have linked CD11b to autoimmune diseases, such as systemic lupus erythematous (SLE).
Cellular Localization
Cell membrane

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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