Anti-S100A10 Mouse mAb

Primary Antibodies

Uncategorized

Ambient temperature

Stable for 12 months from date of receipt/reconstitution.

S100A10 (also known as p11 or calpactin 1 light chain) forms a constitutive heterotetramer with annexin-A2 (ANXA2) and may act as a bridge between the plasma membrane and actin cytoskeleton via interactions with the plasma membrane (via ANXA2) and various protein partners such as the SNARE complex or actin. S100A10 has been hypothesized to play a critical role in neuronal signaling due to its interaction and regulation of neurotransmitter receptors and neuron-specific ion channels such as 5-HT1B, TRPV5, ASIC1, TASK1 and NaV1.8 . More recently, S100A10 has also been shown to modulate macrophage activation and invasion via its ability to bind and transmit receptor-like signals in response to plasminogen.

PBS, Glycerol, BSA

Recombinant Monoclonal

Plasma Membrane, Nucleus, secreted