Vergleich

Anti-LMO4 Rabbit mAb

ArtNr PTM-6651
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB
Clon JMMR-3200
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias LIM domain only protein 4,LMO-4
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
LMO4
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Epigenetics , Cancer
Product description
LMO4 is a LIM zinc-binding domain-containing protein. LMO4 cDNA was first isolated from a breast tumor cDNA library. This transcriptional modulator is overexpressed in several epithelial cancers such as prostate, pancreas, and breast. LMO4 exhibits pro-oncogenic activities by inducing centrosome amplification and mitotic spindle abnormalities. LMO4 is also expressed in the brain, in regions involved in learning and the regulation of motivated behavior. In the basolateral amygdala, LMO4 functions to negatively regulate fear learning. Furthermore, in the nucleus accumbens, LMO4 was found to regulate the behavioral effects of cocaine.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
LMO4 is a LIM zinc-binding domain-containing protein. LMO4 cDNA was first isolated from a breast tumor cDNA library. This transcriptional modulator is overexpressed in several epithelial cancers such as prostate, pancreas, and breast. LMO4 exhibits pro-oncogenic activities by inducing centrosome amplification and mitotic spindle abnormalities. LMO4 is also expressed in the brain, in regions involved in learning and the regulation of motivated behavior. In the basolateral amygdala, LMO4 functions to negatively regulate fear learning. Furthermore, in the nucleus accumbens, LMO4 was found to regulate the behavioral effects of cocaine.
Cellular Localization
Nucleus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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