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Anti-Rab8A Rabbit pAb

Anti-Rab8A Rabbit pAb

ArtNr	PTM-6727
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized powder
Applikationen	WB, ICC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ras-related protein Rab-8A,Oncogene c-mel,MEL,RAB8
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	WB, IHC-P, ICC/IF
Manufacturer - Category	Uncategorized
Manufacturer - Targets	Rab8A
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Signal Transduction
Product description	The RAB8A GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8A is localized to the trans Golgi network (TGN), basolateral membrane, and vesicular structures where it helps regulate target protein transport between TGN and the basolateral membrane. Overexpression studies and mutation analysis of RAB8A and its associated Rab8GEF indicate additional roles in actin and microtubule remodeling during polarized membrane transport and membrane protrusion formation. RAB8A associates with myosin Vb and is required for translocation of GLUT4 following insulin stimulation in muscle. Control of target protein vesicle transport by RAB8A also regulates MT1-MMP activity during extracellular matrix formation and JRAB/MICAL-L2 at tight junction formation.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Polyclonal
Background	The RAB8A GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8A is localized to the trans Golgi network (TGN), basolateral membrane, and vesicular structures where it helps regulate target protein transport between TGN and the basolateral membrane. Overexpression studies and mutation analysis of RAB8A and its associated Rab8GEF indicate additional roles in actin and microtubule remodeling during polarized membrane transport and membrane protrusion formation. RAB8A associates with myosin Vb and is required for translocation of GLUT4 following insulin stimulation in muscle. Control of target protein vesicle transport by RAB8A also regulates MT1-MMP activity during extracellular matrix formation and JRAB/MICAL-L2 at tight junction formation.
Cellular Localization	Cytoplasm, Cytoskeleton, Endosome, Golgi apparatus, Membrane

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

Express-Lieferung: 1 Tage sparen

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