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Anti-TRPV4 Rabbit pAb

Anti-TRPV4 Rabbit pAb

ArtNr	PTM-6728
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized powder
Applikationen	WB, IHC-P
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	OTRPC4,TRP12,Vanilloid receptor-like protein 2,Vanilloid receptor-like channel 2,VR-OAC
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	TRPV4
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Neuroscience
Product description	TRPV4, also named as VRL2 and VROAC, belongs to the transient receptor family and TrpV subfamily. It is a non-selective calcium permeant cation channel protein which involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. It is activated by low pH, citrate and phorbol esters. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Defects in TRPV4 are the cause of brachyolmia type 3 (BRAC3), spondylometaphyseal dysplasia Kozlowski type (SMDK) and metatropic dysplasia (MTD).
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Polyclonal
Background	TRPV4, also named as VRL2 and VROAC, belongs to the transient receptor family and TrpV subfamily. It is a non-selective calcium permeant cation channel protein which involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. It is activated by low pH, citrate and phorbol esters. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Defects in TRPV4 are the cause of brachyolmia type 3 (BRAC3), spondylometaphyseal dysplasia Kozlowski type (SMDK) and metatropic dysplasia (MTD).
Cellular Localization	Cell junction, Cell membrane

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

Express-Lieferung: 1 Tage sparen

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