Anti-AGK Mouse mAb

ArtNr	PTM-6755
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized powder
Applikationen	WB
Clon	JMMR-3556
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Acylglycerol kinase,HsMuLK,Multi-substrate lipid kinase,MULK
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	AGK
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Signal Transduction, Cancer
Product description	Acylglycerol kinase (AGK) is a mitochondrial lipid kinase that phosphorylates monoacylglycerol and diacylglycerol to generate bioactive phospholipids lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Research studies show that the kinase activity of AGK is required for the activation of PI3K-mTOR signaling and the subsequent enhancement of glycolysis in activated CD8+ T cells. AGK is therefore essential for the growth, proliferation and antitumor function of activated CD8+T cells. In addition, AGK is also a subunit of the mitochondrial TIM22 protein import complex independent of its kinase activity. AGK is critical for the stabilization of the TIM22 complex.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	Acylglycerol kinase (AGK) is a mitochondrial lipid kinase that phosphorylates monoacylglycerol and diacylglycerol to generate bioactive phospholipids lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Research studies show that the kinase activity of AGK is required for the activation of PI3K-mTOR signaling and the subsequent enhancement of glycolysis in activated CD8+ T cells. AGK is therefore essential for the growth, proliferation and antitumor function of activated CD8+T cells. In addition, AGK is also a subunit of the mitochondrial TIM22 protein import complex independent of its kinase activity. AGK is critical for the stabilization of the TIM22 complex.
Cellular Localization	Mitochondrion

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

Express-Lieferung: 1 Tage sparen

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