Vergleich

Anti-TrkC Mouse mAb

ArtNr PTM-6852
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB
Clon JMMR-2751
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GP145-TrkC,NTRK3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
TrkC
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Neuroscience, Cancer
Product description
TrkC, also named as NTRK3 (Neurotrophic Receptor Tyrosine Kinase 3), is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
TrkC, also named as NTRK3 (Neurotrophic Receptor Tyrosine Kinase 3), is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Cellular Localization
Membrane

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen