Vergleich

Anti-TGF beta 2 Mouse mAb

ArtNr PTM-7029
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB, IHC-P
Clon JMMR-3632
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Transforming growth factor beta-2 proprotein,LAP,G-TSF
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
TGF beta 2
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Signal Transduction, Stem Cells, Cancer, Metabolism
Product description
TGF-β2 is produced by eosinophils, astrocytes, glioblastoma and other cancer derived cell types. TGF-β2 inhibits antigen-induced T-cell proliferation, inhibits epithelial cell proliferation, induces mesenchymal cell proliferation and has cell specific effects on apoptosis. TGF-β2 binds to TβRII and binding is promoted by TβRIII. TβRI then complexes with TβRII and TβRIII. Signaling involves phosphorylation of the SMAD proteins. TGF-β2 also activates Erk2, p38, and JNK pathways. Knockout of TGF-β2 in mice severely impacts heart, lung and eye development.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
TGF-β2 is produced by eosinophils, astrocytes, glioblastoma and other cancer derived cell types. TGF-β2 inhibits antigen-induced T-cell proliferation, inhibits epithelial cell proliferation, induces mesenchymal cell proliferation and has cell specific effects on apoptosis. TGF-β2 binds to TβRII and binding is promoted by TβRIII. TβRI then complexes with TβRII and TβRIII. Signaling involves phosphorylation of the SMAD proteins. TGF-β2 also activates Erk2, p38, and JNK pathways. Knockout of TGF-β2 in mice severely impacts heart, lung and eye development.
Cellular Localization
Secreted

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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