COVID-19 Rapid Test Kit IgG + IgM (Colloidal Gold)

COVID-19 Rapid Test Kit IgG + IgM (Colloidal Gold) is a qualitative membrane-based immunoassay for the detection of antibodies against SARS-CoV-2 antigens in whole blood, serum or plasma. This test can aid in determining whether or not a subject has been exposed to the novel SARS-CoV-2 coronavirus, which causes the disease COVID-19.

When the mixed sample and buffer solution is added to the sample well, the solution migrates up the test membrane by the capillary effect. If there are anti-SARS-CoV-2 antibodies in the sample, these bind SARS-CoV-2 antigens conjugated to colloidal gold, which are present on the membrane; these migrate together up the membrane to the test line regions. Mouse monoclonal anti-human IgG antibodies are coated on the IgG test line, and these capture any IgG antibodies in the sample, so that capture antibody-sample IgG antibody-antigen-colloidal gold complexes accumulate at the IgG line. Similarly, mouse monoclonal anti-human IgM antibodies coated on the IgM test line can capture any IgM antibodies present in the sample, so that capture antibody-sample IgM antibody-antigen-colloidal gold complexes accumulate at the IgM line. The accumulation of colloidal gold produces a visible line, indicating a positive result for IgG and/or IgM. If the specimen does not contain antibodies to COVID-19, no colored line will appear in either of the test line regions, indicating a negative result. The test results should be read after 10 minutes.

To serve as a procedural control, a colored line will always appear in the control line (C) region, indicating that the proper volume of specimen has been added and membrane wicking has occurred. If the control line is absent, the result is invalid, and should be repeated with a new sample and new cassette.