Milbemycin A3

Blue Ice

528, 7

White lyophilized powder

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is the dominant member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels. Related to: Avermectin B1a, Avermectin B1b, Milbemycin A4, Milbemycin D, Nemadectin.

Source:
Streptomyces hygroscopicus subsp. aureolacrimosus

Synonyms
(6R, 25R)-5-O-Demethyl-28-deoxy-6, 28-epoxy-25-methylmilbemycin B; Spiro[11, 15-methano-2H, 7H, 13H-furo[4, 3, 2-pq][2, 6]benzodioxacyclooctadecin-13, 2’-[2H]pyran], milbemycin B deriv.; (+)-Milbemycin α1; Antibiotic B 41A3; Emamectin A3; GWN 1725; Gowan 1725; Koromite; Matsuguard; Mesa; Mesa (acaricide); Milbeknock; Milbemectin; Milbemycin A3; Milbemycin α1; Ultiflora; Milbemycin EP Impurity B

CAS No:
51596-10-2

Molecular Formula:
C₃₁H₄₄O₇

Molecular Weight:
528.68

Appearance:
White lyophilized powder

Purity:
≥95% by HPLC

Solubility:
Soluble in ethanol, methanol, DMF or DMSO.

Storage and Stability:
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.