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Anti-Acetyllysine Antibody Conjugated Agarose Beads

ArtNr PTM-104
Hersteller PTM Biolabs
Menge 500 ul
Kategorie
Typ Antibody Conjugated Beads
Format Liquid
Applikationen IA
Specific against other
Isotype IgG
Konjugat/Tag Agarose
Dry ice Yes
Citations Xujian Li, et al. Global Insights into the Lysine Acetylome Reveal the Role of Lysine Acetylation in the Adaptation of Bacillus altitudinis to Salt Stress. JOURNAL OF PROTEOME RESEARCH, 2024. https://pubs.acs.org/doi/abs/10.1021/acs.jproteome.4c00581.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 41105507
Alias Kac
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Applications
IAP
Manufacturer - Category
Pan PTM Antibodies
Shipping Temperature
Cold packs / dry ice
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight
Multiple
Stability
Stable for 12 months from date of receipt.
Manufacturer - Research Area
Post-Translational Modificaiton
Manufacturer - Reactivity
All
Product description
The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and gene activities, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. The affinity purification with Anti-Acetyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method for systematical screening of lysine acetylated proteins.
Manufacturer - Specificity
With a mixture of high-quality rabbit- and mouse-derived anti-acetyllysine antibodies cross-linked, this Anti-Acetyllysine Antibody Conjugated Agarose Beads present extraordinary capability to specifically capture peptides/proteins bearing acetyllysine residues but do not cross-react with the peptides/proteins bearing structurally similar propionyllysine or butyryllysine residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine acetylation.
Formula
Antibody conjugated agarose beads are supplied as a 50% slurry containing 66% glycerol and 4 mg/ml immobilized antibody.
PTM
Acetyl
Modification Site
Lys
Immunogen
Acetylated lysine peptides
Clonality
Polyclonal/Monoclonal
Background
The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and gene activities, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. The affinity purification with Anti-Acetyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method for systematical screening of lysine acetylated proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ul
Lieferbar: In stock
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