ArtNr |
PTM-104 |
Hersteller |
PTM Biolabs
|
Menge |
500 ul |
Kategorie |
|
Typ |
Antibody Conjugated Beads |
Format |
Liquid |
Applikationen |
IA |
Specific against |
other |
Isotype |
IgG |
Konjugat/Tag |
Agarose |
Dry ice |
Yes
|
Citations |
Xujian Li, et al. Global Insights into the Lysine Acetylome Reveal the Role of Lysine Acetylation in the Adaptation of Bacillus altitudinis to Salt Stress. JOURNAL OF PROTEOME RESEARCH, 2024. https://pubs.acs.org/doi/abs/10.1021/acs.jproteome.4c00581. |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
41105507 |
Alias |
Kac |
Versandbedingung |
Trockeneis |
Lieferbar |
|
Manufacturer - Type |
Primary Antibodies |
Manufacturer - Applications |
IAP |
Manufacturer - Category |
Pan PTM Antibodies |
Shipping Temperature |
Cold packs / dry ice |
Storage Conditions |
Store at -20°C. Avoid freeze/thaw cycles. |
Molecular Weight |
Multiple |
Stability |
Stable for 12 months from date of receipt. |
Manufacturer - Research Area |
Post-Translational Modificaiton |
Manufacturer - Reactivity |
All |
Product description |
The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and gene activities, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. The affinity purification with Anti-Acetyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method for systematical screening of lysine acetylated proteins. |
Manufacturer - Specificity |
With a mixture of high-quality rabbit- and mouse-derived anti-acetyllysine antibodies cross-linked, this Anti-Acetyllysine Antibody Conjugated Agarose Beads present extraordinary capability to specifically capture peptides/proteins bearing acetyllysine residues but do not cross-react with the peptides/proteins bearing structurally similar propionyllysine or butyryllysine residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine acetylation. |
Formula |
Antibody conjugated agarose beads are supplied as a 50% slurry containing 66% glycerol and 4 mg/ml immobilized antibody. |
PTM |
Acetyl |
Modification Site |
Lys |
Immunogen |
Acetylated lysine peptides |
Clonality |
Polyclonal/Monoclonal |
Background |
The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and gene activities, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. The affinity purification with Anti-Acetyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method for systematical screening of lysine acetylated proteins. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.