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Anti-Glutaryllysine Antibody Conjugated Agarose Beads

Anti-Glutaryllysine Antibody Conjugated Agarose Beads

ArtNr	PTM-1154
Hersteller	PTM Biolabs
Menge	500 ul
Kategorie	Reagents & Chemicals Nanoparticles Beads & Resins
Typ	Antibody Conjugated Beads
Format	Liquid
Applikationen	IA
Specific against	other
Isotype	IgG
Konjugat/Tag	Agarose
Dry ice	Yes
Citations	Longxiang Xie, et al. Proteome-wide Lysine Glutarylation Profiling of the Mycobacterium tuberculosis H37Rv. JOURNAL OF PROTEOME RESEARCH, 2016. https://pubs.acs.org/doi/abs/10.1021/acs.jproteome.5b00917.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	41105507
Alias	Kglu
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	IAP
Manufacturer - Category	Pan PTM Antibodies
Shipping Temperature	Cold packs / dry ice
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	Multiple
Stability	Stable for 12 months from date of receipt.
Manufacturer - Research Area	Post-Translational Modificaiton
Manufacturer - Reactivity	All
Product description	Lysine glutarylation is a histone post-translational modification (PTM) that has been recently identified through integrated proteomic approaches and elaborate biochemistry analyses. This modification has been shown to be evolutionarily conserved across multiple species of prokaryotes and eukaryotes, and is present in a wide range of proteins, including both histones and non-histone substrates. Lysine glutarylation is a PTM that is regulated by SIRT5 and nutrient availability, and it has been demonstrated to impact various metabolic processes and mitochondrial functions.
Manufacturer - Specificity	With the immobilization of highly specific rabbit- and mouse-derived anti-glutaryllysine antibodies, the Anti-Glutaryllysine Antibody Conjugated Agarose Beads present extraordinary capability to selectively capture peptides/proteins bearing glutaryllysine residues but do not cross-react with the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine glutarylation.
Formula	Antibody conjugated agarose beads are supplied as a 50% slurry containing 66% glycerol and 4 mg/ml immobilized antibody.
PTM	Glutaryl
Modification Site	Lys
Immunogen	Glutarylated lysine peptides
Clonality	Polyclonal/Monoclonal
Background	Lysine glutarylation is a histone post-translational modification (PTM) that has been recently identified through integrated proteomic approaches and elaborate biochemistry analyses. This modification has been shown to be evolutionarily conserved across multiple species of prokaryotes and eukaryotes, and is present in a wide range of proteins, including both histones and non-histone substrates. Lysine glutarylation is a PTM that is regulated by SIRT5 and nutrient availability, and it has been demonstrated to impact various metabolic processes and mitochondrial functions.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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PTM-1154-datasheet.pdf

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Menge: 500 ul

lieferbar

Lieferung vsl. bis 27.11.2025

Express-Lieferung: 2 Tage sparen

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