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Anti-RAB7A antibody

Anti-RAB7A antibody

ArtNr	STJ114224-100
Hersteller	St John's Laboratory
Menge	100 ul
Kategorie	Neuroscience Targets for Rodent Neurosciences Antibodies Cell Biology Cytoskeleton Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies small GTPases Ras Subfamily Rab Subfamily
Typ	Antibody Polyclonal
Applikationen	WB, FC, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Ras-Related Protein Rab-7a antibody, Anti-RAB7A RAB7 antibody
Similar products	Anti-Ras-Related Protein Rab-7a antibody Anti-RAB7A RAB7 antibody
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Storage Conditions	Store at 4°C and avoid freeze-thaw cycles.
Molecular Weight	Calculated: 23kDa. Observed: 23kDa
Description	RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic/endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Formulation	PBS with 0.02% sodium azide, pH7.3.
Purification	Affinity purification
Immunogen	Recombinant protein of human RAB7A
Tissue specificity	Widely expressed.high expression found in skeletal muscle.
Cellular localization	Cytoplasmic Vesicle Phagosome Membrane Peripheral Membrane Protein Cytoplasmic Side Late Endosome Membrane Lysosome Membrane Melanosome Membrane Autophagosome Membrane Lipid Droplet Endosome Membrane Colocalizes With Osbpl1a At The Late Endosome Found In The Ruffled Border (A Late Endosomal-Like Compartment In The Plasma Membrane) Of Bone-Resorbing Osteoclasts Recruited To Phagosomes Containing S Aureus Or Mycobacterium Lipid Droplet Localization Is Increased Upon Adrb2 Stimulation
Clonality	Polyclonal
Protein name	Ras-Related Protein Rab-7a
Gene symbol	RAB7A
Dilution range	WB 1:500-1:2000 IHC 1:50-1:100 FC 1:20-1:50
Note	For Research Use Only (RUO).
Short Description	Rabbit polyclonal against RAB7A

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Menge: 100 ul

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