Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ114272-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P05186 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ALPL (NP_000469. 3). |
Short Description |
Rabbit polyclonal against ALPL |
Cellular localization |
Cell MembraneLipid-AnchorGpi-Anchor |
Molecular weight |
Calculated: 48kDa/51kDa/57kDa. Observed: 80kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Alkaline Phosphatase-Tissue-Nonspecific Isozyme antibodyAnti-Ap-Tnap antibodyAnti-Tnsalp antibodyAnti-Alkaline Phosphatase Liver/Bone/Kidney Isozyme antibodyAnti-ALPL antibody |
Protein name |
Alkaline Phosphatase-Tissue-Nonspecific IsozymeAp-TnapTnsalpAlkaline Phosphatase Liver/Bone/Kidney Isozyme |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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