Anti-DBI antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P07108

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium-and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

DBI

Rabbit polyclonal against DBI

Endoplasmic Reticulum
Golgi Apparatus
Golgi Localization Is Dependent On Ligand Binding

WB 1:500-1:2000 IHC 1:50-1:200

Acyl-Coa-Binding Protein
Acbp
Diazepam-Binding Inhibitor
Dbi
Endozepine
Ep

ACBP_HUMAN