Anti-SMAD3 antibody

ArtNr	STJ97434-100
Hersteller	St John's Laboratory
Menge	100 ug
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Mothers Against Decapentaplegic Homolog 3 antibody, Anti-Mad Homolog 3 antibody, Anti-Mad3 antibody, Anti-Mothers Against Dpp Homolog 3 antibody, Anti-Hmad-3 antibody, Anti-Jv15-2 antibody, Anti-Smad Family Member 3 antibody, Anti-Smad 3 antibody, Anti-Smad3 antibody, Anti-Hsmad3 antibody, Anti-SMAD3 MADH3 antibody
Similar products	Anti-Mothers Against Decapentaplegic Homolog 3 antibody Anti-Mad Homolog 3 antibody Anti-Mad3 antibody Anti-Mothers Against Dpp Homolog 3 antibody Anti-Hmad-3 antibody Anti-Jv15-2 antibody Anti-Smad Family Member 3 antibody Ant
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Storage Conditions	Store at-20°C, and avoid repeat freeze-thaw cycles.
Description	Rabbit polyclonal to Smad3.
Formulation	PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Synthesized peptide derived from human Smad3 around the non-phosphorylation site of S213.
Cellular localization	Cytoplasm Nucleus Cytoplasmic And Nuclear In The Absence Of Tgf-Beta On Tgf-Beta Stimulation Migrates To The Nucleus When Complexed With Smad4 Through The Action Of The Phosphatase Ppm1a Released From The Smad2/Smad4 Complex And Exported Out Of The Nucleus By Interaction With Ranbp1 Co-Localizes With Lemd3 At The Nucleus Inner Membrane Mapk-Mediated Phosphorylation Appears To Have No Effect On Nuclear Import Pdpk1 Prevents Its Nuclear Translocation In Response To Tgf-Beta
Clonality	Polyclonal
Protein name	Mothers Against Decapentaplegic Homolog 3 Mad Homolog 3 Mad3 Mothers Against Dpp Homolog 3 Hmad-3 Jv15-2 Smad Family Member 3 Smad 3 Smad3 Hsmad3
Gene symbol	SMAD3
Dilution range	WB 1:500-1:2000 IHC-p 1:50-300
Note	For Research Use Only (RUO).
Short Description	Rabbit polyclonal against Smad3

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Menge: 100 ug

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