Anti-RASD1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q9Y272

This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

RASD1

Rabbit polyclonal against RASD1

Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Cytoplasm
Perinuclear Region
Nucleus

WB 1:200-1:2000

Dexamethasone-Induced Ras-Related Protein 1
Activator Of G-Protein Signaling 1

RASD1_HUMAN