Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Rat |
Isotype |
IgG |
Applikationen |
WB, IHC |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ113716-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P33527 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 850-960 of human ABCC1 (NP_004987. 2). |
Short Description |
Rabbit polyclonal against ABCC1 |
Tissue specificity |
Lung, testis and peripheral blood mononuclear cells. |
Cellular localization |
Cell MembraneMulti-Pass Membrane Protein |
Molecular weight |
Calculated: 151-172kDa. Observed: 210kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Multidrug Resistance-Associated Protein 1 antibodyAnti-Atp-Binding Cassette Sub-Family C Member 1 antibodyAnti-Glutathione-S-Conjugate-Translocating Atpase Abcc1 antibodyAnti-Leukotriene C(4 Transporter antibodyAnti-Ltc4 Transporter antibodyAnti-ABCC1 MRP MRP1 antibody |
Protein name |
Multidrug Resistance-Associated Protein 1Atp-Binding Cassette Sub-Family C Member 1Glutathione-S-Conjugate-Translocating Atpase Abcc1Leukotriene C(4 TransporterLtc4 Transporter |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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