Antibodies

Anti-TNFSF10 Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114198-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Short Description
Rabbit polyclonal to TNFSF10
Alternative names
TNFSF10 antibody
Tumor necrosis factor ligand superfamily member 10 antibody
Apo-2 ligand antibody
Apo-2L antibody
TNF-related apoptosis-inducing ligand antibody
Protein TRAIL antibody
CD antigen CD253 antibody
TNFSF10 antibody
APO2L antibody
TRAIL antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
A synthetic peptide of human TNFSF10
Iso type
IgG
Molecular weight
32.509 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Tissue specificity
Widespread
Uniprot id
P50591

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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