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Anti-TNFSF10 antibody (1-100) Europäischer Partner

ArtNr STJ114198-50
Hersteller St John's Laboratory
Menge 50 ul
Quantity options 100 ul 200 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Tumor Necrosis Factor Ligand Superfamily Member 10 antibody, Anti-Apo-2 Ligand antibody, Anti-Apo-2l antibody, Anti-Tnf-Related Apoptosis-Inducing Ligand antibody, Anti-Protein Trail antibody, Anti-Cd Antigen Cd253 antibody, Anti-TNFSF10 APO2L TRAIL antibody
Similar products Anti-Tumor Necrosis Factor Ligand Superfamily Member 10 antibody
Anti-Apo-2 Ligand antibody
Anti-Apo-2l antibody
Anti-Tnf-Related Apoptosis-Inducing Ligand antibody
Anti-Protein Trail antibody
Anti-Cd Antigen Cd253 antibody
Anti-TN
Lieferbar
Storage Conditions
Store at-20°C and avoid freeze-thaw cycles.
Molecular Weight
Calculated: 11kDa/32kDa.
Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFSF10 (NP_003801. 1).
Tissue specificity
Widespread.most predominant in spleen, lung and prostate.
Cellular localization
Cell Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Exists Both As Membrane-Bound And Soluble Form
Clonality
Polyclonal
Protein name
Tumor Necrosis Factor Ligand Superfamily Member 10
Apo-2 Ligand
Apo-2l
Tnf-Related Apoptosis-Inducing Ligand
Protein Trail
Cd Antigen Cd253
Gene symbol
TNFSF10
Dilution range
WB 1:500-1:2000
Note
For Research Use Only (RUO).
Short Description
Rabbit polyclonal against TNFSF10

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: Out of stock
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