Antibodies

Anti-TNFSF10 antibody

Kein Verkauf an Patienten, Ärzte, Apotheken oder Privatpersonen! Mehr erfahren

204,00 €
Zzgl. MwSt.
Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human
Isotype IgG
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114198-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P50591
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
Gene symbol
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFSF10 (NP_003801. 1).
Short Description
Rabbit polyclonal against TNFSF10
Tissue specificity
Widespread.most predominant in spleen, lung and prostate.
Cellular localization
Cell Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Exists Both As Membrane-Bound And Soluble Form
Molecular weight
Calculated: 11kDa/32kDa.
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Tumor Necrosis Factor Ligand Superfamily Member 10 antibody
Anti-Apo-2 Ligand antibody
Anti-Apo-2l antibody
Anti-Tnf-Related Apoptosis-Inducing Ligand antibody
Anti-Protein Trail antibody
Anti-Cd Antigen Cd253 antibody
Anti-TNFSF10 APO2L TRAIL antibody
Protein name
Tumor Necrosis Factor Ligand Superfamily Member 10
Apo-2 Ligand
Apo-2l
Tnf-Related Apoptosis-Inducing Ligand
Protein Trail
Cd Antigen Cd253
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt und Sicherheitsdatenblatt) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Menge: 50ul
Lieferbar: In stock
Listenpreis: 204,00 €
Preis: 204,00 €
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen