Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Applikationen |
IF |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
STJ115335-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P50461 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human CSRP3 (NP_003467. 1). |
Short Description |
Rabbit polyclonal against CSRP3 |
Tissue specificity |
Cardiac and slow-twitch skeletal muscles. Isoform 2 is expressed in striated muscle. Isoform 2 is specifically expressed at higher levels in patients with neuromuscular diseases, such as limb-girdle muscular dystrophy 2A (LGMD2A), Duchenne muscular dystrophy (DMD) and dermatomyositis. |
Cellular localization |
NucleusCytoplasmCytoskeletonMyofibrilSarcomereZ LineNucleocytoplasmic Shuttling ProteinMainly CytoplasmicIn The Z LineFound Associated With Glrx3Isoform 2: Cytoplasm |
Molecular weight |
Calculated: 6kDa/20kDa. Observed: |
Dilution range |
IF 1:50-1:200 |
Alternative names |
Anti-Cysteine And Glycine-Rich Protein 3 antibodyAnti-Cardiac Lim Protein antibodyAnti-Cysteine-Rich Protein 3 antibodyAnti-Crp3 antibodyAnti-Lim Domain Protein-Cardiac antibodyAnti-Muscle Lim Protein antibodyAnti-CSRP3 CLP MLP antibody |
Protein name |
Cysteine And Glycine-Rich Protein 3Cardiac Lim ProteinCysteine-Rich Protein 3Crp3Lim Domain Protein-CardiacMuscle Lim Protein |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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