Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Mouse, Rat |
Isotype |
IgG |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ114202-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P18433 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 529-793 of human PTPRA (NP_543031. 1). |
Short Description |
Rabbit polyclonal against PTPRA |
Cellular localization |
Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionFocal AdhesionLocalizes To Focal Adhesion Sites Following Integrin Engagement |
Molecular weight |
Calculated: 89kDa/90kDa. Observed: 145kDa/160kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Receptor-Type Tyrosine-Protein Phosphatase Alpha antibodyAnti-Protein-Tyrosine Phosphatase Alpha antibodyAnti-R-Ptp-Alpha antibodyAnti-PTPRA PTPA PTPRL2 antibody |
Protein name |
Receptor-Type Tyrosine-Protein Phosphatase AlphaProtein-Tyrosine Phosphatase AlphaR-Ptp-Alpha |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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