Octyl-alpha-ketoglutarate

Hersteller Toronto Research Chemicals
Kategorie
Typ Biochemicals
Specific against other
Menge 5mg
ArtNr TRC-O288175-5mg
Eclass 6.1 32160405
Eclass 9.0 32160490
Lieferbar
Synonym
2-Oxo-pentanedioic Acid 1-Octyl Ester; alpha-KG Octyl Ester
CAS Number
876150-14-0
Mol. Formula
C13H22O5
Mol. Weight
258, 31
Melting Pt.
N/A
Application Notes
Octyl-alpha-ketoglutarate is a prolyl hydroxylases substrate which accumulates rapidly in cells with dysfunctional tricarboxylic acid cycle. Octyl-alpha-ketoglutarate also prevents succinate or fumarate mediated inhibition of prolyl hydroxylases.
References
MacKenzie, E.D., et al.: Mol. Cell Biol., 27, 3282 (2007);
Menge: 5mg
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