PTEN-induced Kinase 1 (PTEN-induced Putative Kinase 1, PTEN-induced Putative Kinase Protein 1, PINK1, PINK-1, BRPK, FLJ27236, PARK6, Serine/threonine Protein Kinase PINK1 Mitochondrial)

Antibodies / Antibodies-Protein Kinases

-20°C

Tris-citrate/phosphate, [pH7-8].

An N-terminal region synthetic peptide made to the human Pink1 protein sequence (between residues 1-50). Homology: 100% homology with human and mouse protein.

Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids. Malfunctions in this contribute to many human cancers. PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers. It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease.

Cellular Localization: Mitochondrion.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.