SERPINI1 (Neuroserpin, CLADE I, Protease Inhibitor 12, PI12, Serine or Cysteine Proteinase Inhibitor Clade I Member 1)

Antibodies / Antibodies-Protease Inhibitors

-20°C

Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.

NS0-derived recombinant, human Serpin I1. (aa 19-410) (Accession#: Q99574)

Serpin I1, also known as neuroserpin, is a secreted serine protease inhibitor predominantly expressed in the brain. Serpin I1 defects cause familial encephalopathy with neuroserpin inclusion bodies (FEN1B), an autosomal dominant dementia.

Applications:
Suitable for use in Direct ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Direct ELISA: 0. 5-1.0ug/ml. Detection limit is ~3ng/well.
Western Blot: 1-2ug/ml. Detection limit is ~25ng/lane under non-reducing and reducing conditions.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.