HPSE2, CT (HPSE2, HPA2, Inactive heparanase-2)

Antibodies / Antibodies-Enzymes, Heparanase

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-480 amino acids from the C-terminal region of human HPSE2.

Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1, 000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.