DAND5 (DAN domain family member 5,CER2,Cerberus-like protein 2,CERL2,Cerl-2,CKTSF1B3,COCO,CRL2,Cysteine knot superfamily 1,BMP antagonist 3,DAN domain family member 5,DANTE,DTE,FLJ38607,GREM3,Gremlin-3,MGC126849,SP1) (Bi

Antibodies / Antibodies-Growth Factors, Cytokines

-20°C

Supplied as a lyophilized powder from PBS, 5% BSA. Labeled with Biotin. Reconstitute with 500ul sterile PBS.

Purified, E. coli-derived, recombinant human DAND5 (aa23-189; Accession # NP_689867).

DAND5, also known as COCO, Dante, and CKTSF1B3, is a member of the DAN Domain family of BMP antagonists that includes DAN, Gremlin, PRDC, and Cerberus. DAND5 binds and inhibits Xnr1, BMP-4, Activin, and Wnt8. It is implicated in gastrulation and embryonic left-right axis formation. Human DAND5 shares 60% and 24% aa sequence identity with mouse and Xenopus DAND5, respectively.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA (Detection): 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.

Matched Pair:
Capture: D1038-08A
Detection: D1038-08

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.