PARK 7 (DJ-1)

Antibodies / Antibodies-Oncoproteins

-20°C

Supplied as a liquid in PBS, pH 7.2.

Synthetic peptide (AAQVKAPLVLKD) corresponding to aa178-189 of human PARK 7

PARK 7, also known as DJ-1 is a highly conserved cytoplasmatic protein and acts as a positive regulator of androgen receptor-dependent transcription. The expression of PARK 7 is induced by growth signals, and it is translocated from the cytoplasm to nucleous during S-phase of the cell cycle. PARK 7 also may fuction as redox-sensitive chaperone and as sensor for oxidative stress. Mutations in PARK 7 are associated with the autosomal recessive early-onset Parkinson's disease.

Applications:
Suitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1000
Western Blot: 1:1000
Immunocytochemistry: 1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.