LRP5, CT (LRP5, LR3, LRP7, Low-density lipoprotein receptor-related protein 5)

Antibodies / Antibodies-Lipoproteins

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1162-1190 amino acids from the C-terminal region of human LRP5.

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1, 000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.