Insulin-like 5 (Insulin-like Peptide 5, INSL5, PRO182, MGC126695, MGC126697, UNQ156)

Antibodies / Antibodies-Insulin

-20°C

Supplied as a lyophilized powder from PBS. Reconstitute with 100ul sterile PBS.

Synthetic peptide corresponding to the A and B chain of mouse Insulin-like 5

Insulin gene superfamily hormones modulate metabolism, cell growth and tissue-specific functions. Members of this superfamily are characterized by a signal peptide, a B chain, a connecting C chain and an A chain. Insulin-like peptides (INSL proteins), also designated Relaxin-like factors, are mostly secreted proteins that are expressed mainly in testis, placenta, uterus or prenatal tissues. The human 135 amino acid INSL5 protein, which shares 40% and 59% sequence homology with human RLN1 and mouse INSL5, respectively, contains a dibasic cleavage site between the B and C chains. INSL5 exists as a heterodimer of a B chain and an A chain which are linked by two disulfide bonds. INSL5 is thought to play a role in gut contractility or in thymic development and regulation.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilutions:
ELISA: 1:1600 (0.625ug/ml)
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.