c-Fos (Fos)

Antibodies / Antibodies-Oncoproteins

-20°C

Supplied as a lyophilized powder. Reconstitute in 50ul of sterile water. Centrifuge to remove any insoluble material.

Synthetic peptide (MFSGFNADYEASSSRC; aa 2-17) conjugated to diphtheria toxoid

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. Belongs to the bZIP family. Fos subfamily.

Applications:
Suitable for use in ELISA. Other applications not tested.

Subcellular Localization: Nucleus.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.