MKP1 Rabbit pAb

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.

A synthetic peptide corresponding to a sequence within amino acids 267-367 of human MKP1 (NP_004408.1).

Signal Transduction, Kinase, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway.

1843

DUSP1