Galectin 3/LGALS3 Rabbit mAb

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Galectin 3/LGALS3 (NP_002297.2).

Epigenetics Nuclear Signaling, RNA Binding, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Cell Adhesion, Neuroscience.

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LGALS3