RAF1 (pY341) Antibody

RAF1 (pY341)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

PBS containing 0.09% sodium azide.

This product is for research use only.

RAF1_HUMAN