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26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Antibody

Hersteller Abbexa
Kategorie
Typ Antibody Primary
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB, IF, IHC, ICC
Menge 50 ul
Host Rabbit
ArtNr abx141928-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Antigen
26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
Description
PSMD8 Antibody is a Rabbit Polyclonal against PSMD8. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
Purification
Affinity chromatography.
Storage
Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC
P48556
UniProt Entry Name
PSMD8_HUMAN
Gene Symbol
PSMD8
Gene ID
5714, 57296
Buffer
0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol and 0.01% sodium azide.
Dry Ice
No
Note
This product is for research use only.

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Menge: 50 ul
Lieferbar: Out of stock
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