Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) Antibody

PTPN22 Antibody is a Rabbit Polyclonal antibody against PTPN22. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Affinity purified.

Q9Y2R2

PTPN22

Calculated MW: 20 kDa, 75 kDa, 78 kDa, 85 kDa, 88 kDa, 91 kDa
Observed MW: 107 kDa

No