X-Ray Repair Cross Complementing 5 (XRCC5) Antibody

X-Ray Repair Cross Complementing 5 (XRCC5)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

PBS containing 0.09% sodium azide.

This product is for research use only.

XRCC5_HUMAN