Zinc Finger Protein Aiolos (IKZF3) Antibody

Zinc Finger Protein Aiolos (IKZF3)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

PBS containing 0.09% sodium azide.

IKZF3

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Cow IKZF3.