Human Tissue Transglutaminase (TGM2) Protein

Tissue Transglutaminase (TGM2)

Human Tissue Transglutaminase (TGM2) Enzyme is a recombinant enzyme produced in Sf9 insect cells. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

This product is for research use only.

Not for human consumption, cosmetic, therapeutic or diagnostic use.

Recombinant