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DMPK Polyclonal Antibody

DMPK Polyclonal Antibody

ArtNr	ABK-ABP51181-30ul
Hersteller	Abbkine Scientific
Menge	30 ul
Quantity options	100 ul 200 ul 30 ul
Kategorie	Oncology Antibodies Western Blot ELISA Primary Antibodies By Organ Skin Cancer
Typ	Antibody Polyclonal
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DMPK,DM1PK,MDPK,Myotonin-protein kinase,MT-PK,DM-kinase,DMK,DM1 protein kinase,DMPK,Myotonic dystrophy protein kinase
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Manufacturer - Applications	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
Shipping Temperature	Gel pack with blue ice.
Storage Conditions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Background	Dystrophia myotonica protein kinase encoded by DMPK is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5, 000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of DMPK have been described, but the full-length nature of some of these variants has not been determined.
Formulation	Liquid solution
Immunogen	Synthesized peptide derived from the N-terminal region of human DMPK at AA range: 30-110
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration	1 mg/ml
Other information	DMPK Polyclonal Antibody detects endogenous levels of DMPK protein.
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABK-ABP51181-30ul-datasheet.pdf

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Menge: 30 ul

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Lieferung vsl. bis 01.01.2026

Express-Lieferung: 7 Tage sparen

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