Napsin A Polyclonal Antibody

Gel pack with blue ice.

NAPSA encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. NAPSA has been described as a marker for lung adenocarcinoma and renal cell carcinoma.

Synthesized peptide derived from part region of human Napsin A protein at amino acid sequence of 191-240

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

The antibody detects endogenous levels of Napsin A