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SMC1B Polyclonal Antibody

SMC1B Polyclonal Antibody

ArtNr	ABK-ABP60442-200ul
Hersteller	Abbkine Scientific
Menge	200 ul
Quantity options	100 ul 200 ul 30 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Structural maintenance of chromosomes protein 1B,SMC protein 1B,SMC-1-beta,SMC-1B
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Manufacturer - Applications	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Shipping Temperature	Gel pack with blue ice.
Storage Conditions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Background	SMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).
Formulation	Liquid solution
Immunogen	Synthesized peptide derived from part region of human SMC1B protein at amino acid sequence of 110-190
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Concentration	1 mg/ml
Other information	The antibody detects endogenous levels of SMC1B protein
Storage Buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 200 ul

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Lieferung vsl. bis 01.01.2026

Express-Lieferung: 7 Tage sparen

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