hnRNP H Polyclonal Antibody

Gel pack with blue ice.

HNRNPH2 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. Heterogeneous nuclear ribonucleoprotein H2 encoded by HNRNPH2 has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.

Synthesized peptide derived from the Internal region of human hnRNP H at AA range: 130-210

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

hnRNP H Polyclonal Antibody detects endogenous levels of hnRNP H protein.