Axl Polyclonal Antibody

Gel pack with blue ice.

The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.

Synthesized peptide derived from human Axl around the non-phosphorylation site of Y697

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Axl Polyclonal Antibody detects endogenous levels of Axl protein.