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Anti-COBRA1 (NELF-B) Antibody

ArtNr ABC-AN1339
Hersteller Abcepta
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Clon F7E4
Specific against Cattle (Bovine)
Host Mouse
Isotype IgG1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias A730008L03Rik antibody,AB041607 antibody,AI663983 antibody,Cofactor of BRCA1 antibody,DKFZp586B0519 antibody,KIAA1182 antibody,Negative elongation factor B antibody,Negative elongation factor protein B antibody,Nelf b antibody,NELF-B antibody,NELFB antibody,RGD1307832 antibody,RP13-122B23.3 antibody,RP23-132N23.4 antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Bio Background
COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ER?) and repress ER?-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Clonality
Monoclonal
Gene Name
NELFB
Subtitle
Our Anti-COBRA1 (NELF-B) primary antibody from PhosphoSolutions is mouse monoclonal. It detects huma
Reactivity
B
Calculated Molecular Weight
65697
Formulation
Protein G Purified

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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