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Anti-COBRA1 (NELF-B) Antibody

Anti-COBRA1 (NELF-B) Antibody

Item no.	ABC-AN1339
Manufacturer	Abcepta
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma By Organ Bladder Cancer Breast Cancer Neuronal Cell Markers
Type	Antibody Monoclonal
Clone	F7E4
Specific against	Cattle (Bovine)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	A730008L03Rik antibody,AB041607 antibody,AI663983 antibody,Cofactor of BRCA1 antibody,DKFZp586B0519 antibody,KIAA1182 antibody,Negative elongation factor B antibody,Negative elongation factor protein B antibody,Nelf b antibody,NELF-B antibody,NELFB antibody,RGD1307832 antibody,RP13-122B23.3 antibody,RP23-132N23.4 antibody
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Bio Background	COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ER?) and repress ER?-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Clonality	Monoclonal
Gene Name	NELFB
Subtitle	Our Anti-COBRA1 (NELF-B) primary antibody from PhosphoSolutions is mouse monoclonal. It detects huma
Reactivity	B
Calculated Molecular Weight	65697
Formulation	Protein G Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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