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Anti-FMRP (Ser499) Antibody

Anti-FMRP (Ser499) Antibody

ArtNr	ABC-AN1385
Hersteller	Abcepta
Menge	100 ul
Kategorie	Neuroscience Neural Transcription Factors Molecular Targets for Neuroscience Western Blot
Applikationen	WB
Specific against	Cat (Feline, Felis catus), Cattle (Bovine)
Host	Rabbit
Isotype	IgG
Alias	FMR 1 antibody,Fmr1 antibody,Fmr1 gene antibody,FMR1_HUMAN antibody,FMRP antibody,Fragile X mental retardation 1 antibody,Fragile X mental retardation 1 protein antibody,Fragile X mental retardation protein 1 antibody,Fragile X mental retardation protein antibody,fragile X mental retardation syndrome-related protein 1 antibody,fragile X mental retardation autosomal homolog 1 antibody,FRAXA antibody,fxr1 antibody,MGC87458 antibody,POF antibody,POF1 antibody,Protein FMR-1 antibody,Protein FMR1 antibody,wu:fb16f11 antibody,wu:fd18c10 antibody,zgc:66226 antibody
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Manufacturer - Category	Primary Antibodies; Neuroscience
Manufacturer - Targets	Fragile X Mental Retardation Protein (FMRP) is an RNA-binding protein that plays an essential role in cognitive brain function. Mutations in the FMR1 gene, which codes for FMRP, can result in fragile X syndrome, autism, as well as other cognitive deficits (Brown et al., 1998, Goodlin-Jones et al., 2004). Phosphorylation of the highly conserved Ser-499 has been shown to trigger hierarchical phosphorylation of nearby serines and may play a role in suppressing target mRNA translation (Ceman et al., 2003, Narayanan et al. 2008).
Bio Background	Fragile X Mental Retardation Protein (FMRP) is an RNA-binding protein that plays an essential role in cognitive brain function. Mutations in the FMR1 gene, which codes for FMRP, can result in fragile X syndrome, autism, as well as other cognitive deficits (Brown et al., 1998, Goodlin-Jones et al., 2004). Phosphorylation of the highly conserved Ser-499 has been shown to trigger hierarchical phosphorylation of nearby serines and may play a role in suppressing target mRNA translation (Ceman et al., 2003, Narayanan et al. 2008).
Clonality	Polyclonal
Gene Name	Fmr1 {ECO:0000312\|RGD:2623}
Subtitle	Our Anti-FMRP (Ser499) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is p
Reactivity	B, C
Calculated Molecular Weight	66780
Formulation	Antigen Affinity Purified from Pooled Serum

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 06.11.2025

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