« Back
Home /
Anti-FMRP (Ser499) Antibody

Anti-FMRP (Ser499) Antibody

Item no.	ABC-AN1385
Manufacturer	Abcepta
Amount	100 ul
Category	Neuroscience Neural Transcription Factors Molecular Targets for Neuroscience Western Blot
Applications	WB
Specific against	Cat (Feline, Felis catus), Cattle (Bovine)
Host	Rabbit
Isotype	IgG
Alias	FMR 1 antibody,Fmr1 antibody,Fmr1 gene antibody,FMR1_HUMAN antibody,FMRP antibody,Fragile X mental retardation 1 antibody,Fragile X mental retardation 1 protein antibody,Fragile X mental retardation protein 1 antibody,Fragile X mental retardation protein antibody,fragile X mental retardation syndrome-related protein 1 antibody,fragile X mental retardation autosomal homolog 1 antibody,FRAXA antibody,fxr1 antibody,MGC87458 antibody,POF antibody,POF1 antibody,Protein FMR-1 antibody,Protein FMR1 antibody,wu:fb16f11 antibody,wu:fd18c10 antibody,zgc:66226 antibody
Available
Manufacturer - Category	Primary Antibodies; Neuroscience
Manufacturer - Targets	Fragile X Mental Retardation Protein (FMRP) is an RNA-binding protein that plays an essential role in cognitive brain function. Mutations in the FMR1 gene, which codes for FMRP, can result in fragile X syndrome, autism, as well as other cognitive deficits (Brown et al., 1998, Goodlin-Jones et al., 2004). Phosphorylation of the highly conserved Ser-499 has been shown to trigger hierarchical phosphorylation of nearby serines and may play a role in suppressing target mRNA translation (Ceman et al., 2003, Narayanan et al. 2008).
Bio Background	Fragile X Mental Retardation Protein (FMRP) is an RNA-binding protein that plays an essential role in cognitive brain function. Mutations in the FMR1 gene, which codes for FMRP, can result in fragile X syndrome, autism, as well as other cognitive deficits (Brown et al., 1998, Goodlin-Jones et al., 2004). Phosphorylation of the highly conserved Ser-499 has been shown to trigger hierarchical phosphorylation of nearby serines and may play a role in suppressing target mRNA translation (Ceman et al., 2003, Narayanan et al. 2008).
Clonality	Polyclonal
Gene Name	Fmr1 {ECO:0000312\|RGD:2623}
Subtitle	Our Anti-FMRP (Ser499) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is p
Reactivity	B, C
Calculated Molecular Weight	66780
Formulation	Antigen Affinity Purified from Pooled Serum

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AN1385-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 11/6/2025

Express Delivery: Save 10 days

Compare

Add to wishlist

Get an offer