ATG4B Rabbit mAb

Monoclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ATG4B (Q9Y4P1).

44kDa

Cancer, Invasion and metastasis, Signal transduction, Cell biology developmental biology, Autophagy, Extracellular matrix, Ubiquitin, Endocrine metabolism, Mitochondrial metabolism, Cardiovascular, Heart.

23192

ATG4B